Wednesday, February 10, 2016

CDC-Oxford ‘Death Gene’ Is Key To The Brazilian Babies Riddle

The mobilization of 500,000 soldiers and public-health workers to spray pesticides across Brazil is effectively terminating a controversial British-American biotechnology project that has released millions of gene-engineered mosquitoes in a backfired experiment to combat the dengue fever virus (DENV). The Oxitec gene-manipulation technique called RIDL (Release of Insects carrying a Dominant Lethal) is widely suspected of spreading a new virulent strain of ZIKA virus, and the Brazilian outbreak in turn raises fears of a link to microcephaly or reduced brain size in human embryos. (Oxitec is a corporate spinoff of Oxford University, even though most of its researchers are with less prestigious British schools or from the United States.)
First of all, this essay explains how the recent cases of Brazilian microcephaly were not caused by ZIKA but are instead a “side effect” of the RIDL gene-transfer. The so-called Death Gene blockage, using the GATA binding protein, can affect the same gene in human embryos as in the targeted mosquito pupae. The OX513-A captive mosquito program releases protein-carrier male mosquitoes to mate with the wild local female mosquitoes. The lethal protein enters the eggs to disrupt embyonic growth, causing the offspring to self-destruct (auto-side) before they reach adulthood. However, these same mother mosquitoes can then transfer the dangerous protein into women, thereby seriously harming human embryonic development of the brain, nerves, heart and testicles. Damage to the GATA-1 protein in human embryos is associated with Down Syndrome, a brain disorder similar to Brazilian microcephaly. (While there are many other causes of microcephaly, the new Brazil type is extraordinarily severe.)
Second, as many critics of the Oxitec program have suggested, the captive mosquito population is “leaky”, with a survival rate of between 0.5 and 5 percent. In theory, the dengue virus (and the similar arbovirus ZIKA) should not be capable of replicating in the RIDL protein-tainted saliva of the wild female mosquitoes. In the field, however, humans inside the OX513-A test area continue to be infected with mosquito-transmitted ZIKA virus. As the lethal acronym suggests, the Oxitec method is riddled with flaws. These disturbing issues raise the possibility of the existence of a hidden agenda behind the Oxitec program, that is, to spread an embryo-death gene in Brazilian women for the purpose of a covert population-reduction program.
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